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phenobarbital will lessen the level or result of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.phenobarbital will decrease the extent or impact of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Double brexpiprazole dose above one-2 weeks if adm